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Three fractions (JMR1, JMR2 and JMR3) obtained from the methanolic extract of Lantana wightiana have been tested against the fourth instar larvae of Spodoptera litura. From the results it is evident that JMR1, JMR2 and JMR3 caused 100 % mortality during 96 h at 0.1%. At 0.0125%, JMR1 causes 80% mortality after 24 h of S. litura larvae. But similar percentage of mortality has been observed when 0.08% crude methanolic extract of L. wightiana treated with S. litura larvae. Total mortality of S. litura shows that JMR1 is the most effective toxic fraction followed by JMR2 and then JMR3. Comparison between JMR2 to JMR1 and JMR2 to JMR3 are statistically insignificant at 5% level by Duncan Multiple Range test (DMRT). When a correlation is made between the concentrations and total mortality, it is found to be highly significant [r = 0.98, 0. 97 and 0.93 for JMR1, 2 and 3, respectively]. It is evident from the results that JMR1 is found to be the most effective (0.0057%) to S. litura larvae followed by JMR2 (0.0092%) and then JMR 3 (0.0094%). It is very clear from the results that the LC50 value of L. wightiana fraction, JMR1 is about 3 times more effective than the crude methanolic extract on the fourth instar Spodoptera litura larvae.
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