The objective of the present study is to evaluate the antimicrobial potency of five solvents (petroleum ether, benzene, chloroform, methanol and water) extracts of five medicinal ferns Pteris biaurita L., Lygodium flexiuosam (L.) Sw., Hemionitis arifolia (Burm.F.) T. Moore, Actinopteris radiata (J. Koenig ex Sw.) Link and Adiantum latifolium Lam. against the gram negative plant pathogenic bacteria Xanthomonas campestris. Antimicrobial activity, Minimum Inhibitory Concentration (MIC) and Relative Percentage Inhibition (RPI) value of the extracts against X. campestris were screened according to the standard procedures. Among the twenty five tested

extracts, methanol and benzene extracts of P. biaurita showed significant inhibition (p<0.05) against the tested bacteria. Based on the results of MIC (8µg/mL) and RPI (199.36%) values, it could be concluded that P. biaurita can be used as potential plant for the management of X. campestris which is known to cause leaf spot disease on many vegetables and cash crops particularly Centella asiatica.